When your car, your spine, or even the stars are out of alignment, it means that the elements that must come together for a successful drive, walk, or karma are instead working independently, and not moving you toward your goal. Every inch of progress is a struggle, and success is more difficult than it has to be.
Are all parts of your organization operating in an alignment with the overall company objectives? If not how do you go about analyzing the real issues and creating better alignment? Alignment begins with Leadership and communicating the mission, vision and objectives through a series of cadence meetings and performance reviews on an ongoing basis, working to align the organization and get all the parts working in unison.